SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Unipolar Depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.030 GeneticVariation disease BEFREE Major depressive disorder-associated SIRT1 locus affects the risk for suicide in women after middle age. 31176830 2019
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.030 AlteredExpression disease BEFREE A recent genome-wide association study has identified a locus for major depression in the Sirtuin1 gene (SIRT1) and lower blood levels of SIRT1 mRNA in patients with depression have also been observed in two studies. 30017261 2018
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		0.030 Biomarker disease BEFREE SIRT1 gene is associated with major depressive disorder in the Japanese population. 20451257 2010