SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Tumor necrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333516
Disease: Tumor necrosis
Tumor necrosis 		0.010 Biomarker phenotype BEFREE In the present study, we demonstrated that the NAD<sup>+</sup>-dependent histone deacetylase SIRT1 (silent mating type information regulation 2 homolog 1) plays a key role in the permissivity of prostate cancer PC-3 cells to VSVΔM51 replication and oncolysis. 31092575 2019