FOLH1, folate hydrolase 1, 2346

N. diseases: 311; N. variants: 20
Disease: tumor vasculature ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.020 AlteredExpression phenotype BEFREE It was hypothesized that PSMA-mediated activation of mipsagargin would result in disruption of the tumor vasculature, leading to a decrease in blood flow, and in direct cytotoxic effects on tumor cells, resulting in anti-tumor activity. 31212948 2019
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.020 AlteredExpression phenotype BEFREE All (100%) cases of primary ovarian carcinoma, ovarian carcinoma metastases, and primary endometrial carcinoma showed PSMA expression in tumor vasculature, which was diffuse in majority of cases. 26862945 2017