FOLH1, folate hydrolase 1, 2346

N. diseases: 311; N. variants: 20
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 GeneticVariation disease BEFREE However, localizing a BCR with PSMA PET/CT remains challenging in patients with low prostate-specific antigen (PSA) values. 31481580 2020
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE A total of 93 patients with biochemically recurrent prostate cancer underwent [<sup>68</sup>Ga]PSMA-11 PET/CT and subsequently a whole-body integrated PET/MRI examination. 31482413 2019
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Prostate specific membrane antigen targeted radiotracers are likely effective to detect biochemically recurrent prostate cancer at low prostate specific antigen levels. 30829130 2019
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 GeneticVariation disease BEFREE In this single-arm prospective trial conducted at University of California, San Francisco and University of California, Los Angeles, 635 patients with biochemically recurrent prostate cancer after prostatectomy (n = 262, 41%), radiation therapy (n = 169, 27%), or both (n = 204, 32%) underwent 68Ga-PSMA-11 PET. 30920593 2019
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Ga-labeled prostate-specific membrane antigen inhibitors and Ga-labeled gastrin-releasing peptide receptor antagonists showed interesting results for staging biochemically recurrent prostate cancer. 31246685 2019
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Prostate-specific membrane antigen (PSMA) PET/CT is increasingly used in patients with biochemically recurrent prostate cancer (BCR), mostly using gallium-68 (<sup>168</sup>Ga)-labelled radiotracers. 31230088 2019
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE The use of <sup>68</sup>Ga-PET/CT PSMA to determine patterns of disease for biochemically recurrent prostate cancer following primary radiotherapy. 31363165 2019
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Clinical impact of PSMA-based <sup>18</sup>F-DCFBC PET/CT imaging in patients with biochemically recurrent prostate cancer after primary local therapy. 28894899 2018
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Imaging of biochemically recurrent prostate cancer has been established as a widely accepted clinical indication for PSMA ligand PET/CT in many parts of the world because of the results of multiple, primarily retrospective, studies that indicate superior detection efficacy compared with standard-of-care imaging. 28687599 2017
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Optimal MRI sequences for <sup>68</sup>Ga-PSMA-11 PET/MRI in evaluation of biochemically recurrent prostate cancer. 28929350 2017
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Impact of <sup>68</sup>Ga-PSMA-11 PET on Management in Patients with Biochemically Recurrent Prostate Cancer. 28522741 2017
CUI: C4759295
Disease: Non-metastatic prostate cancer
Non-metastatic prostate cancer
0.100 Biomarker disease BEFREE Since biochemically recurrent prostate cancer is defined by technological limitations of radiographic detection, as new imaging (i.e., PSMA) strategies are developed, it may alter how the disease is monitored and perhaps managed. 28434181 2017