PADI4, peptidyl arginine deiminase 4, 23569

N. diseases: 196; N. variants: 20
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE TSP-4 levels increased with PAD severity and showed a former unknown association with diabetes. 31227875 2020
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 AlteredExpression group BEFREE Anti-PAD4 Ab levels in CF sera associated with lung infection by P. aeruginosa, but not that by S. aureus, age, sex, CF-related diabetes or the presence of musculoskeletal pain. 30638826 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE Middle or old age, obesity, ABI and diabetes mellitus were risk factors for the Han population, smoking was a risk factor in the Uygur population, and obesity and PAD were risk factors in the Kazakh population. 29346374 2018
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 GeneticVariation group BEFREE Participants with both diabetes and CHD had 2.75-fold increased odds of PAD (95% CI 2.66-2.85). 28224925 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 GeneticVariation group BEFREE ACEI = angiotensin-converting enzyme inhibitors; ADA = American Diabetes Association; ARB = angiotensin-receptor blocker; CAD = coronary artery disease; Cr = creatinine; CVD = cardiovascular disease; DM = diabetes mellitus; HF = heart failure; HT = hypertension; JNC = Joint National Committee; KAUH = King Abdullah University Hospital; LV = left ventricular; PAD = peripheral artery disease; RAAS = renin-angiotensin-aldosterone system; TIA = transient ischemic attack. 28816537 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.060 Biomarker group BEFREE In the multivariate analysis, age, male sex and diabetes duration were independent risk factors for PAD and PVD (P < 0.01). 23331854 2013