|
Crohn Disease
|
0.310 |
AlteredExpression
|
disease |
BEFREE |
Finally, we found that FPR2 gene expression was increased approximately sixfold in the colon of patients with Crohn's disease, a finding reproduced in vitro by the treatment of THP-1 cells with interferon-γ or lipopolysaccharide.
|
21659618 |
2011 |
|
Crohn Disease
|
0.310 |
Biomarker
|
disease |
CTD_human |
Finally, we found that FPR2 gene expression was increased approximately sixfold in the colon of patients with Crohn's disease, a finding reproduced in vitro by the treatment of THP-1 cells with interferon-γ or lipopolysaccharide.
|
21659618 |
2011 |
|
Crohn's disease of large bowel
|
0.300 |
Biomarker
|
disease |
CTD_human |
Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production.
|
21659618 |
2011 |
|
Crohn's disease of the ileum
|
0.300 |
Biomarker
|
disease |
CTD_human |
Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production.
|
21659618 |
2011 |
|
Regional enteritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production.
|
21659618 |
2011 |
|
IIeocolitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production.
|
21659618 |
2011 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
RNA sequencing (RNA-seq) analyses of the RFP+ and GFP+ hepatocyte populations after tumor regression confirmed the conversion of tumor cells to normal hepatocytes, as most of the genes and pathways that were deregulated in the tumor stages were found to have normal regulation in the tumor-reverted hepatocytes.
|
31515263 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In the present study, we showed that when GFP labelled BMMSCs and RFP labelled HCC1806 cells are injected together <i>in vivo</i>, they create tumors which contain a new hybrid cell that has characteristics of both BMMSCs and HCC1806 cells.
|
31191817 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The positive correlation between ANXA1/FPR2 and ANXA1/MMP-9 was observed in all tumors studied.
|
30286327 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In a previous report, we developed color-coded imaging of the tumor microenvironment (TME) of the murine EL4-RFP malignant lymphoma during metastasis, including the lung.
|
28668831 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
We previously described a zebrafish optic pathway tumor model in which transgenic Tg(flk1:RFP)is18/+ adults develop nonmalignant retinal tumors.
|
28192065 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Then, RFP-Eca-109 burdened nude mice model was constructed, and were treated with ALA-PDT when the tumor volume reached 150-350mm<sup>3</sup>.
|
28811223 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
OBP-401 was then injected into high-metastatic MDA-MB-231-RFP primary orthotopic tumor growing in mice which already had developed metastasis within lymphatic ducts.
|
27863373 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Tumor IS were only of prognostic value for the sequentially endocrine-treated patients (RFP: p = 0.035, HR intermediate IS 1.420, 95% CI 0.878-2.297; HR low IS 1.657, 95% CI 1.131-2.428; BCSS: p = 0.002, HR intermediate IS 2.486, 95% CI 1.375-4.495; HR low IS 2.422, 95% CI 1.439-4.076; and OS: p = 0.005, HR intermediate IS 1.509, 95% CI 0.950-2.395; HR low IS 1.848, 95% CI 1.277-2.675).
|
25616355 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In the present study, human glioma stem/progenitor cells transfected with red fluorescent protein gene (SU3‑RFP) were seeded inside the abdominal cavity of transgenic nude mice, of which all nucleated cells could express green fluorescent protein (GFP), forming a tumor model with a double‑color RFP/GFP fluorescent tracer.
|
25483261 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The hybrid cells in xenografted tumor were identified by FISH and GFP/RFP dual-immunofluoresence staining.
|
25016285 |
2014 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The size of the primary tumor and RFP intensity of lung metastasis were measured.
|
19221501 |
2009 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Expression of both GFP and RFP under control of HIP-1 demonstrated an approximately 15-fold increase relative to a constitutive promoter when tumors were made hypoxic.
|
16855381 |
2006 |
|
Tumor Cell Invasion
|
0.080 |
AlteredExpression
|
phenotype |
BEFREE |
These findings indicated that FPR2 overexpression alters proliferation, migration and invasion in human extravillous trophoblastic cellsthrough the ILK/NF-κB signaling pathway; ideal FPR2 levels are important for TEV-1 cells functions.
|
31176799 |
2019 |
|
Tumor Cell Invasion
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
FPR2-knockdown significantly abrogated the migration and invasion stimulated by Hp(2-20) and Ac(2-26), two well-characterized ligands for FPR2 in GC cells.
|
28600569 |
2017 |
|
Tumor Cell Invasion
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
The present study suggested that FPR2 promoted the invasion and metastasis of EOC and it could be a prognostic marker for EOC.
|
29039544 |
2017 |
|
Tumor Cell Invasion
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Using in vitro immunofluorescence and live microscopy with ex vivo macrophage cultures from RFP-Lifeact mice, we show that cytotoxic necrotizing factor 1 (CNF1) secreted by E. coli K1 sequesters cellular actin toward microspike formation, thereby limiting actin availability for OmpA-mediated bacterial invasion.
|
27221788 |
2016 |
|
Tumor Cell Invasion
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Agonists, inhibitors or siRNA of formyl peptide receptor like‑1 (FPRL‑1), mitogen‑activated protein kinases and αvβ3 integrin were used to investigate the mechanism underlying the effects of SAA on the regulation of U2OS cell migration and invasion.
|
25323768 |
2014 |
|
Tumor Cell Invasion
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Together, our results provide evidence that ECRG2 regulates invasion/migration partly through ECM degradation and uPA/uPAR/FPRL1 pathway, and may represent a novel therapeutic target for cancer.
|
19796867 |
2010 |
|
Tumor Cell Invasion
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
By contrast, FPRL1 was required for LL-37-induced invasion through Matrigel.
|
19491199 |
2009 |