Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE High expression of cystine-glutamate antiporter xCT (SLC7A11) is an independent biomarker for epileptic seizures at diagnosis in glioma. 29404978 2018
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE Stable SLC7A11 knockdown and overexpressing U251 glioma cells were generated and characterized to understand the role of redox and system x<sub>c</sub><sup>-</sup> in glioma progression. 28610554 2017
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE SLC7A11, in addition to redox modulation, appears to be associated with increased cellular metabolism and is a mediator of temozolomide resistance in human glioma, thus making system x<sub>C</sub><sup>-</sup> a potential therapeutic target in glioblastoma multiforme. 27658422 2016