RAB38, RAB38, member RAS oncogene family, 23682

N. diseases: 34; N. variants: 17
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 Biomarker disease BEFREE Together, these data establish a novel targeted proteomic method for interrogating the small GTPase proteome in human cells and identify epigenetic reactivation of RAB38 as a contributing factor to metastatic transformation in melanoma.<b>Significance:</b> A novel quantitative proteomic method leads to the discovery of RAB38 as a new driver of metastasis in melanoma.<i></i>. 30072397 2018
CUI: C0025202
Disease: melanoma
melanoma 		0.020 AlteredExpression disease BEFREE Consistent with this lineage specificity, rab38 mRNA is expressed in 80-90% of melanoma (17 of 19), but rarely in nonmelanocytic malignancies (1 of 16). 10910072 2000