RAB38, RAB38, member RAS oncogene family, 23682

N. diseases: 34; N. variants: 17
Disease: Neoplasm Metastasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.020 Biomarker phenotype BEFREE These results suggest that <i>RAB38</i> is an important prognostic factor in NSCLC, and may serve a critical role in NSCLC-associated tumor metastasis. 31452745 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.020 Biomarker phenotype BEFREE Together, these data establish a novel targeted proteomic method for interrogating the small GTPase proteome in human cells and identify epigenetic reactivation of RAB38 as a contributing factor to metastatic transformation in melanoma.<b>Significance:</b> A novel quantitative proteomic method leads to the discovery of RAB38 as a new driver of metastasis in melanoma.<i></i>. 30072397 2018