APOL2, apolipoprotein L2, 23780

N. diseases: 20; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.410 Biomarker disease BEFREE By applying ICSNPathway analysis to schizophrenia GWAS data, we identified candidate SNPs, genes like KCNQ2 and APOL2 and pathways involving the estrogen biosynthetic process may contribute to schizophrenia susceptibility. 23644028 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.410 Biomarker disease CTD_human
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.410 Biomarker disease HPO
CUI: C0006868
Disease: Cannabis Abuse
Cannabis Abuse 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0006870
Disease: Cannabis Dependence
Cannabis Dependence 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0018614
Disease: Hashish Abuse
Hashish Abuse 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0024809
Disease: Marijuana Abuse
Marijuana Abuse 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0031391
Disease: Phencyclidine Abuse
Phencyclidine Abuse 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0236735
Disease: Cannabis-Related Disorder
Cannabis-Related Disorder 		0.300 Biomarker group CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.300 Biomarker group CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0236742
Disease: Phencyclidine-Related Disorders
Phencyclidine-Related Disorders 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.300 Biomarker disease CTD_human Transcriptional changes common to human cocaine, cannabis and phencyclidine abuse. 17205118 2006
CUI: C0011253
Disease: Delusions
Delusions 		0.100 Biomarker disease HPO
CUI: C0018524
Disease: Hallucinations
Hallucinations 		0.100 Biomarker disease HPO
CUI: C0027562
Disease: Negativism
Negativism 		0.100 Biomarker phenotype HPO
CUI: C1866986
Disease: Social and occupational deterioration
Social and occupational deterioration 		0.100 Biomarker phenotype HPO
CUI: C0001956
Disease: Alcohol Use Disorder
Alcohol Use Disorder 		0.010 GeneticVariation disease BEFREE The genome-wide meta-analysis of EAA in AUD revealed a significant single nucleotide polymorphism (SNP), rs916264 (p = 5.43 × 10<sup>-8</sup>), in apolipoprotein L2 (APOL2) at the genome-wide level. 31466081 2020
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.010 Biomarker disease BEFREE Regions of the salience network, including the mid cingulate cortex, and mid and superior temporal gyrus were positively correlated with several pro-inflammatory genes (interleukin 6, APOL2) in IBS, but negatively correlated with several anti-inflammatory genes (KRT8, APOA4) in HCs. 28191693 2017
CUI: C2062441
Disease: Influenza A
Influenza A 		0.010 AlteredExpression disease BEFREE ApoL2 mRNA expression was also elevated in normal human lung fibroblasts and smooth muscle cells stimulated with IFN-γ, in lung tissues from an IFN-γ-predominant influenza A virus-infected mouse lung injury model, and in cancer lung tissues from human patients. 20665705 2011
CUI: C0023645
Disease: Lichen planus follicularis
Lichen planus follicularis 		0.010 AlteredExpression disease BEFREE Specific genes, such as MMP11, TNFSF13B, and APOL2, were identified with significantly differential expression in association with LPP versus PPB. 19932600 2010
CUI: C1266144
Disease: Pleuropulmonary blastoma
Pleuropulmonary blastoma 		0.010 AlteredExpression disease BEFREE Specific genes, such as MMP11, TNFSF13B, and APOL2, were identified with significantly differential expression in association with LPP versus PPB. 19932600 2010