ALK, ALK receptor tyrosine kinase, 238

N. diseases: 519; N. variants: 41
Disease: Pleural effusion disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032227
Disease: Pleural effusion disorder
Pleural effusion disorder 		0.050 Biomarker group BEFREE We report a case of recurrence of anaplastic lymphoma kinase (ALK) rearrangement-positive lung adenocarcinoma with increased cellular pleomorphism and ALK copy number in pleural effusion cytology, and retrospectively compared the recurrent tumor with the primary tumor in terms of cytological features, immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). 29637735 2018
CUI: C0032227
Disease: Pleural effusion disorder
Pleural effusion disorder 		0.050 Biomarker group BEFREE ALK-positive NSCLC had more brain metastasis and less pleural effusion than double-negative ones. 28374971 2017
CUI: C0032227
Disease: Pleural effusion disorder
Pleural effusion disorder 		0.050 GeneticVariation group BEFREE ALK rearrangements were associated with age and pleural effusion. 25956936 2016
CUI: C0032227
Disease: Pleural effusion disorder
Pleural effusion disorder 		0.050 GeneticVariation group BEFREE EML4-ALK rearrangement in pleural effusions has a predictive value for treatment. 27060609 2016
CUI: C0032227
Disease: Pleural effusion disorder
Pleural effusion disorder 		0.050 Biomarker group BEFREE ALK+ status was associated with central tumor location, absence of pleural tail, and large pleural effusion. 24885982 2014