ALK, ALK receptor tyrosine kinase, 238

N. diseases: 519; N. variants: 41
Disease: Septicemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE Here, we investigated the therapeutic potential of an anaplastic lymphoma kinase inhibitor, LDK378, in cecal ligation and puncture (CLP)-induced polymicrobial sepsis and examined its effects on the recruitment of MDSCs. 31472096 2019
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE LDK378, a second-generation ALK inhibitor, exhibits a potential anti-inflammatory function against sepsis. 30820191 2019
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE Comment on "ALK is a therapeutic target for lethal sepsis". 30541790 2018
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 Biomarker disease BEFREE Response to comment on "ALK is a therapeutic target for lethal sepsis". 30541792 2018
CUI: C0036690
Disease: Septicemia
Septicemia 		0.050 AlteredExpression disease BEFREE The ALK pathway is up-regulated in patients with sepsis. 29046432 2017