ALOX5, arachidonate 5-lipoxygenase, 240

N. diseases: 342; N. variants: 16
Disease: ASA intolerant asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0543699
Disease: ASA intolerant asthma
ASA intolerant asthma 		0.020 GeneticVariation disease BEFREE Although the alleles of the ALOX5 and ALOX5AP promoter cannot be considered as a prominent risk factor in the development of AIA, the genetic variant of tandem repeat (GGGCGG; Sp1-binding motif) in ALOX5 promoter is associated with the severity of airway hyperresponsiveness in AIA patients. 15876305 2005
CUI: C0543699
Disease: ASA intolerant asthma
ASA intolerant asthma 		0.020 GeneticVariation disease BEFREE However, the possible involvement of ALOX5-ht1[G-C-G-A] in AIA development is suggested. 14749922 2004