ALOX15, arachidonate 15-lipoxygenase, 246

N. diseases: 205; N. variants: 5
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 AlteredExpression disease BEFREE These results indicated that PLGF up-regulation by 15-LOX downstream product may be involved in inflammatory arthritis. 23872401 2013
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 AlteredExpression disease BEFREE In comparison with wild-type mice, adjuvant-induced arthritis and MMP-2 expression in synovial membrane were markedly inhibited in 15-LOX knockout (KO) mice. 22573549 2012
CUI: C0003864
Disease: Arthritis
Arthritis 		0.030 Biomarker disease BEFREE Reticulocyte-type 15-lipoxygenase-1 (ALOX15) has anti-inflammatory and inflammatory effects and is implicated in the development of asthma, arthritis and atherosclerosis. 17439326 2007