IL27, interleukin 27, 246778

N. diseases: 286; N. variants: 14
Disease: Tuberculous pleural effusion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2959467
Disease: Tuberculous pleural effusion
Tuberculous pleural effusion 		0.030 Biomarker disease BEFREE Exogenous intrapleural injection of interleukin-27 may improves outcome and prognosis in patients with tuberculous pleural effusion. 31443751 2019
CUI: C2959467
Disease: Tuberculous pleural effusion
Tuberculous pleural effusion 		0.030 Biomarker disease BEFREE With a cut-off value of 591.4 ng/L in the Beijing cohort, the area under the curve, sensitivity, specificity, positive predictive value and negative predictive value of interleukin 27 to diagnose TPE were 0.983 (95% CI 0.947 to 0.997), 96.1% (86.5% to 99.5%), 99.0% (94.7% to 100%), 98.0 (89.4 to 99.9) and 98.1 (93.3 to 99.8), respectively. 28844060 2018
CUI: C2959467
Disease: Tuberculous pleural effusion
Tuberculous pleural effusion 		0.030 Biomarker disease BEFREE The summary assessments for IL-27 in the diagnosis between TPE and MPE were: SEN 0.93 (95% CI 0.90-0.96), SPE 0.97 (95% CI 0.94-0.98), PLR 25.88 (95% CI 13.84-48.39), NLR 0.07 (95% CI 0.05-0.11), and DOR 333.26 (95% CI 146.10-760.19), respectively. 29539604 2018