MTOR, mechanistic target of rapamycin kinase, 2475

N. diseases: 960; N. variants: 48
Disease: Lichen Planus, Oral ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral 		0.030 AlteredExpression disease BEFREE Expressions of mTOR, 4E-BP1, PLD2 and Hif-1α mRNA were significantly reduced in peripheral T lymphocytes of OLP patients, especially in erosive form. mTOR expression was positively correlated with PLD2 and Hif-1α expression in OLP. 30419486 2019
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral 		0.030 Biomarker disease BEFREE This study investigated the possible function of IGF1-PI3K/AKT/MTOR pathway in the local immunity of OLP. 30773287 2019
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral 		0.030 AlteredExpression disease BEFREE In conclusion, the present study demonstrated that miR‑199 and miR‑122 are implicated in the pathogenesis of OLP by regulating the expression of mTOR and AKT1. 30664152 2019