MTOR, mechanistic target of rapamycin kinase, 2475

N. diseases: 960; N. variants: 48
Disease: Inflammatory dermatosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3875321
Disease: Inflammatory dermatosis
Inflammatory dermatosis 		0.020 Biomarker disease BEFREE We produced models of skin inflammation induced by imiquimod (IMQ) and IL-23 and tested the effect of inhibiting LAT1 (JPH203) and mammalian target of rapamycin (mTOR [rapamycin]). 31605740 2020
CUI: C3875321
Disease: Inflammatory dermatosis
Inflammatory dermatosis 		0.020 Biomarker disease BEFREE Taken together, our results demonstrate that the mTOR-STAT3 signaling differentially regulates dermal γδT cell effector function in skin inflammation. 31167146 2019