Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1279296
Disease: Chronic leukemia (category)
Chronic leukemia (category)
0.010 Biomarker disease BEFREE The excessive proliferation of the myeloid marrow compartment in Philadelphia chromosome (Ph)-positive acute and chronic leukemias has been largely attributed to a hyperactive and autonomously acting hybrid tyrosine kinase BCR-ABL, a product of the fusion between the second exon of the c-ABL proto-oncogene and 5' portions of the BCR gene on chromosome 22. 9676840 1998