Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 AlteredExpression disease BEFREE Their effects on cerebral ischemia and underlying mechanisms remain inconclusive; however, increasing evidence indicates the involvement of the transcriptional factor Nrf2. 31494826 2020
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE These results suggested that tBHQ enhanced angiogenesis and astrocyte activation through activating Nrf2 pathway after cerebral ischemia. 31283926 2019
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Nomilin protects against cerebral ischemia-reperfusion induced neurological deficits and blood-brain barrier disruption via the Nrf2 pathway. 31389456 2019
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Influences of urinary kallidinogenase on neuronal apoptosis in cerebral infarction rats through Nrf2/ARE oxidative stress pathway. 31378909 2019
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Nrf2/ARE pathway inhibits ROS-induced NLRP3 inflammasome activation in BV2 cells after cerebral ischemia reperfusion. 28956063 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Protective effects of 8-MOP on blood-brain barrier via the Nrf-2/HO-1 pathway in mice model of cerebral infarction. 30024618 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Meanwhile, it increased the cerebral ischemia-reperfusion injury by changing the distribution of Nrf2. 29917204 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE These studies offer new targets and pathways of Nrf2, which may be heavily implicated following cerebral ischemia. 29103101 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Systemic administration of UTI attenuated autophagy and apoptosis, and largely restored Nrf2-ARE signal pathway following cerebral ischemia and thereby alleviated neurological deficits with increasing survival of CA rats. 29750875 2018
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Intranasal Pretreatment with Z-Ligustilide, the Main Volatile Component of Rhizoma Chuanxiong, Confers Prophylaxis against Cerebral Ischemia via Nrf2 and HSP70 Signaling Pathways. 28169530 2017
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Effects of Estradiol on Autophagy and Nrf-2/ARE Signals after Cerebral Ischemia. 28419990 2017
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE 5-HMF attenuates striatum oxidative damage via Nrf2/ARE signaling pathway following transient global cerebral ischemia. 27812888 2017
CUI: C0007785
Disease: Cerebral Infarction
Cerebral Infarction
0.100 Biomarker disease BEFREE Antioxidant and pro-angiogenic effects of corilagin in rat cerebral ischemia via Nrf2 activation. 29383122 2017