Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036646
Disease: Age-related cataract
Age-related cataract
0.020 Biomarker disease BEFREE Age-related cataracts: homocysteine coupled endoplasmic reticulum stress and suppression of Nrf2-dependent antioxidant protection. 22964297 2012
CUI: C0036646
Disease: Age-related cataract
Age-related cataract
0.020 GeneticVariation disease BEFREE We hypothesize that common variants of NFE2L2 and KEAP1, the genes encoding the main regulators of the Nrf2 system, an important defence system against oxidative stress, may influence risk of AD and/or age-related cataract. 20064547 2010