GAD1, glutamate decarboxylase 1, 2571

N. diseases: 245; N. variants: 14
Disease: Prediabetes syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome 		0.020 Biomarker disease BEFREE The 65KD isoform of GAD is considered to be a major target autoantigen in many humans with autoimmune prediabetes or diabetes. 10078545 1999
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome 		0.020 Biomarker disease BEFREE By immunoprecipitation of recombinant GAD65 and GAD67 protein and protein fragments, 83% of sera from individuals with new-onset diabetes or prediabetes (n = 30) had GAD65 autoantibodies, but only 26% had GAD67 autoantibodies. 8039604 1994