SUN2, Sad1 and UNC84 domain containing 2, 25777

N. diseases: 33; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.030 Biomarker disease BEFREE SUN2 Modulates HIV-1 Infection and Latency through Association with Lamin A/C To Maintain the Repressive Chromatin. 29717016 2018
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.030 Biomarker disease BEFREE Taken together, these observations suggest that SUN1 and SUN2 may function redundantly to modulate postentry, nuclear-associated steps of HIV-1 infection.<b>IMPORTANCE</b> HIV-1 causes more than 1 million deaths per year. 28747499 2017
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
0.030 Biomarker disease BEFREE SUN2 Silencing Impairs CD4 T Cell Proliferation and Alters Sensitivity to HIV-1 Infection Independently of Cyclophilin A. 28077629 2017