BRI3, brain protein I3, 25798

N. diseases: 10; N. variants: 1
Disease: Neuritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027813
Disease: Neuritis
Neuritis 		0.020 Biomarker disease BEFREE However, in SH-SY5Y cells, BRI2 and BRI3 could also be detected in elongated cellular projections ('processes') and in rat cortical neurons both are broadly distributed throughout the cell body, neuritis and the nucleus. 26515131 2016
CUI: C0027813
Disease: Neuritis
Neuritis 		0.020 Biomarker disease BEFREE BRI3 colocalizes with APP along neuritis in differentiated N2a cells; endogenous BRI3-APP complexes are readily detectable in mouse brain extract; reducing endogenous BRI3 levels by RNA interference results in increased Abeta secretion. 19366692 2009