BACE2, beta-secretase 2, 25825

N. diseases: 54; N. variants: 6
Disease: Senile Plaques ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		0.020 Biomarker disease BEFREE BACE2 is an aspartyl protease to cleave APP to prevent the generation of Aβ, a central component of neuritic plaques in Alzheimer's brain. 29703946 2018
CUI: C0333463
Disease: Senile Plaques
Senile Plaques 		0.020 Biomarker disease BEFREE Our data argue against BACE2 being involved in the formation of neuritic plaques in AD. 15857888 2005