Disease: Epilepsy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.230 Biomarker disease BEFREE Further, nuclear accumulation of GluA2 and GAPDH have been studied in neurological disorders like epilepsy and multiple sclerosis, and disruption of this complex rescued neurological symptoms such as astrogliosis, AMPA mediated excitotoxicity and p53 phosphorylation. 31759082 2020
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.230 Biomarker disease BEFREE The GluA2/GAPDH interaction may be a novel therapeutic target for epilepsy. 29489588 2018
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.230 Biomarker disease RGD The GluR2/GAPDH complex co-internalizes upon stimulation of AMPARs, which might be involved in the development of epilepsy. 30143487 2018
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.230 AlteredExpression disease BEFREE Taken together, these data suggest that GAPDH-mediated expression regulation of sodium channel genes may be associated with epilepsy and the anticonvulsant action of KD. 27816501 2017