Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We found that the combination of TP4 and p38 inhibitors (SB202190 and VX-745) enhanced cytotoxicity in U251 glioblastoma cells but not noncancerous neural cells.
|
31673920 |
2020 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition - implications for the next generation of DC vaccines.
|
31143512 |
2019 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Ultrasound enhanced anti-tumor effect of temozolomide in glioblastoma cells <i>via</i> JNK and p38 pathways.
|
31719901 |
2019 |
Childhood Glioblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Moreover, TP4 induced mitochondrial hyperpolarization and dysfunction, which preceded the elevation of intracellular reactive oxygen species, DNA damage, and necrotic cell death in both U87MG and U251 glioblastoma cells. p38 was also activated by TP4, but did not contribute to cytotoxicity.
|
30717309 |
2019 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mutual Stabilization between TRIM9 Short Isoform and MKK6 Potentiates p38 Signaling to Synergistically Suppress Glioblastoma Progression.
|
29669288 |
2018 |
Childhood Glioblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
C-27-carboxylated oleanane triterpenoids up-regulate TRAIL DISC assembly via p38 MAPK and CHOP-mediated DR5 expression in human glioblastoma cells.
|
30359578 |
2018 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
RUNX1 Regulates Migration, Invasion, and Angiogenesis via p38 MAPK Pathway in Human Glioblastoma.
|
28012022 |
2017 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Alisertib induces G<sub>2</sub>/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cells.
|
28386317 |
2017 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Oncogenic Ras modulates p38 MAPK-mediated inflammatory cytokine production in glioblastoma cells.
|
26794430 |
2016 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Apoptotic Effects of Cordycepin Through the Extrinsic Pathway and p38 MAPK Activation in Human Glioblastoma U87MG Cells.
|
26597532 |
2016 |
Childhood Glioblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Proteasome inhibitor MG132 induces NAG-1/GDF15 expression through the p38 MAPK pathway in glioblastoma cells.
|
23261467 |
2013 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here we report that IL-1β, IL-6, and IL-8 levels and p38 MAPK activity are elevated in human glioblastoma specimens and that p38 MAPK inhibitors attenuate the secretion of pro-inflammatory cytokines by microglia and glioblastoma cells.
|
22528800 |
2012 |
Childhood Glioblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Specific inhibition of the β1 integrin or proliferation-associated signaling molecules revealed a critical function of JNK, PI3K, and p38 MAPK in glioblastoma cell invasion.
|
22901381 |
2012 |