|
Congenital heart disease
|
0.200 |
Biomarker
|
group |
BEFREE |
Results showed that NKX2.5, GATA4, and FOG2 were susceptibility genes of congenital heart disease.
|
27118988 |
2016 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Mutations of NKX2.5 and GATA4 genes in the development of congenital heart disease.
|
27154817 |
2016 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
A Novel Missense Mutation of GATA4 in a Chinese Family with Congenital Heart Disease.
|
27391137 |
2016 |
|
Congenital heart disease
|
0.200 |
CausalMutation
|
group |
CLINVAR |
Congenital heart diseases and their association with the variant distribution features on susceptibility genes.
|
27426723 |
2017 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Using induced pluripotent stem cells, Ang et al. elucidate how a mutation in the transcription factor GATA4 causes congenital heart disease.
|
27984717 |
2016 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Dominant GATA4 mutations cause congenital heart disease (CHD), specifically atrial and atrioventricular septal defects (ASDs and AVSDs).
|
28167794 |
2017 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Three GATA4 gene mutations, 99 G>T, 487 C>T, and 354 A>C, have been reported in congenital heart disease (CHD).
|
28471988 |
2017 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Identification of intronic-splice site mutations in GATA4 gene in Indian patients with congenital heart disease.
|
28843068 |
2017 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Functional mutant GATA4 identification and potential application in preimplantation diagnosis of congenital heart diseases.
|
29111206 |
2018 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Search of Somatic Mutations of NKX2-5 and GATA4 Genes in Chinese Patients with Sporadic Congenital Heart Disease.
|
30121862 |
2019 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Familial ASDs and other forms of congenital heart disease may be seen with mutations in associated myocardial transcription factors NKX2.5, GATA4, TBX6, along with conduction disorders such as AV block.
|
30305954 |
2018 |
|
Congenital heart disease
|
0.200 |
Biomarker
|
group |
BEFREE |
GATA4 is an important transcription factor involved in cardiac development and a well-known candidate gene associated with congenital heart disease (CHD).
|
30590232 |
2019 |
|
Congenital heart disease
|
0.200 |
Biomarker
|
group |
BEFREE |
NKX2-5 and GATA4 were the first congenital heart disease-causing genes identified by linkage analysis.
|
30834692 |
2019 |
|
Congenital heart disease
|
0.200 |
Biomarker
|
group |
BEFREE |
GATA4 screening in Iranian patients of various ethnicities affected with congenital heart disease: Co-occurrence of a novel de novo translocation (5;7) and a likely pathogenic heterozygous GATA4 mutation in a family with autosomal dominant congenital heart disease.
|
31115957 |
2019 |
|
Congenital heart disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Functional analysis of the congenital heart disease‑associated GATA4 H436Y mutation in vitro.
|
31322241 |
2019 |