GATA4, GATA binding protein 4, 2626

N. diseases: 336; N. variants: 72
Disease: granulosa cell tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018206
Disease: granulosa cell tumor
granulosa cell tumor 		0.030 AlteredExpression disease BEFREE Aberrant ovarian granulosa cell proliferation and apoptosis may lead to granulosa cell tumors (GCT), the pathogenesis of which involves transcription factors GATA4, FOXL2, and SMAD3. 24416423 2014
CUI: C0018206
Disease: granulosa cell tumor
granulosa cell tumor 		0.030 AlteredExpression disease BEFREE GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumors. 18653721 2008
CUI: C0018206
Disease: granulosa cell tumor
granulosa cell tumor 		0.030 AlteredExpression disease LHGDN In contrast, GATA-4 expression was high (i.e. resembled normal granulosa cells) in 44% of GCTs and correlated positively with clinical stage and recurrence (P = 0.0232 and P = 0.0038, respectively). 16159935 2005