FGF21, fibroblast growth factor 21, 26291

N. diseases: 236; N. variants: 2
Disease: Kidney Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.050 Biomarker group BEFREE Thus, FGF21 may be a potential therapeutic target for the treatment of kidney disease, although adverse side effects should also be considered when administering FGF21 since FGF21 may affect bone development and reproduction. 29108880 2019
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.050 Biomarker group BEFREE The observational and associative human data contrast sharply with in vitro and in vivo preclinical experimental data, which is more in line with a protective role of FGF21 in chronic nephropathies. 30430412 2019
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.050 Biomarker group BEFREE Both osteonectin and FGF21 were associated with early nephropathy in T2DM patients, albeit with different patterns. 27916484 2017
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.050 Biomarker group BEFREE Fibroblast growth factor 21 (FGF21), a hepatoadipokine with pleiotropic metabolic regulatory actions, is emerging as a novel biomarker of progressive nephropathy. 28181108 2017
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.050 AlteredExpression group BEFREE However, FGF21 level was not significantly associated with nephropathy after multivariable adjustment. 27839924 2017