FGF21, fibroblast growth factor 21, 26291

N. diseases: 236; N. variants: 2
Disease: Chondrodysplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0343284
Disease: Chondrodysplasia
Chondrodysplasia 		0.010 Biomarker disease BEFREE Chondrocyte survival is enabled, cell autonomously, by CHOP and dual CHOP-ATF4 transactivation of <i>Fgf21.</i> Treatment of mutant mice with a chemical inhibitor of PERK signaling prevents the differentiation defects and ameliorates chondrodysplasia. 30024379 2018