GCK, glucokinase, 2645

N. diseases: 210; N. variants: 182
Disease: Prediabetes syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome 		0.030 GeneticVariation disease BEFREE A genetic variant near the glucokinase gene (rs4607517) was significantly associated with progression to prediabetes or diabetes (hazard ratio 1·27, 1·16-1·38; p=1·70 × 10(-7)). 26577716 2016
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome 		0.030 GeneticVariation disease BEFREE We aimed to assess the prevalence of diabetic retinopathy (DR) in adult patients with GCK-MODY and HNF1A-MODY in Poland and to identify biochemical and clinical risk factors associated with its occurrence.We examined 74 GCK mutation carriers, 51 with diabetes and 23 with prediabetes, respectively, and 63 patients with HNF1A-MODY. 26240958 2015
CUI: C0362046
Disease: Prediabetes syndrome
Prediabetes syndrome 		0.030 GeneticVariation disease BEFREE This study evaluated the effect of the quantity of dietary carbohydrate on glucose levels in 10 GCK mutation carriers: seven with MODY and three with prediabetes. 22289546 2011