OPN1MW, opsin 1, medium wave sensitive, 2652

N. diseases: 107; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.070 Biomarker phenotype BEFREE Add-on THC:CBD oromucosal spray provided better and clinically relevant improvement of resistant MS spasticity compared with adjusting first-line antispasticity medication alone. 29792372 2019
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.070 GeneticVariation phenotype BEFREE The influence of physiotherapy intervention on patients with multiple sclerosis-related spasticity treated with nabiximols (THC:CBD oromucosal spray). 31361750 2019
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.070 Biomarker phenotype BEFREE Second-line therapy includes add-on THC:CBD spray for patients with resistant MS spasticity. 30235965 2018
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.070 Biomarker phenotype BEFREE The majority of patients reported an improvement in driving ability after starting THC:CBD oromucosal spray, and it was speculated that this may be related to reduced spasticity and/or better cognitive function. 29761015 2018
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.070 Biomarker phenotype BEFREE In study B, 55 MS patients treated with THC:CBD oromucosal spray for their resistant spasticity were followed prospectively. 27904961 2017
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.070 Biomarker phenotype BEFREE A randomised controlled cross-over double-blind pilot study protocol on THC:CBD oromucosal spray efficacy as an add-on therapy for post-stroke spasticity. 28882919 2017
CUI: C0026838
Disease: Muscle Spasticity
Muscle Spasticity
0.070 Biomarker phenotype BEFREE Expert commentary: From the different therapeutic possibilities, THC/CBD oromucosal spray has been in clinical use for approximately five years in numerous countries world-wide for the management of multiple sclerosis (MS)-related moderate to severe resistant spasticity. 28276775 2017