AGO1, argonaute RISC component 1, 26523

N. diseases: 48; N. variants: 2
Disease: Global developmental delay ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0557874
Disease: Global developmental delay
Global developmental delay 		0.320 AlteredExpression disease BEFREE However, downregulation of Argonaute 1 reduced larval survivorship and delayed development. 29891360 2018
CUI: C0557874
Disease: Global developmental delay
Global developmental delay 		0.320 Biomarker disease GENOMICS_ENGLAND Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder. 29346770 2018
CUI: C0557874
Disease: Global developmental delay
Global developmental delay 		0.320 GeneticVariation disease BEFREE We describe five patients with hypotonia, poor feeding, and developmental delay who were found to have microdeletions of chromosomal region 1p34.3 encompassing the AGO1 and AGO3 genes. 25271087 2015