Marijuana Abuse
|
0.310 |
Biomarker
|
disease |
PSYGENET |
The G allele of SNP rs596359, in the RGS17 promoter region, was associated with AD, CD, OD, or MjD in both populations (0.005≤P(empirical)≤0.019).
|
22591552 |
2012 |
Marijuana Abuse
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
The G allele of SNP rs596359, in the RGS17 promoter region, was associated with AD, CD, OD, or MjD in both populations (0.005≤P(empirical)≤0.019).
|
22591552 |
2012 |
Amphetamine Addiction
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genome-wide association for methamphetamine dependence: convergent results from 2 samples.
|
18316681 |
2008 |
Amphetamine Abuse
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genome-wide association for methamphetamine dependence: convergent results from 2 samples.
|
18316681 |
2008 |
Malignant neoplasm of prostate
|
0.140 |
GeneticVariation
|
disease |
GWASDB |
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
|
23535732 |
2013 |
Malignant neoplasm of prostate
|
0.140 |
Biomarker
|
disease |
BEFREE |
Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures.
|
29351497 |
2018 |
Malignant neoplasm of prostate
|
0.140 |
Biomarker
|
disease |
BEFREE |
Our findings revealed that miR-203/RGS17 axis might be a potential therapeutic target for the treatment of PCa.
|
31298318 |
2019 |
Malignant neoplasm of prostate
|
0.140 |
Biomarker
|
disease |
BEFREE |
Two compounds, sanguinarine (1) and celastrol (2), were found to be cytostatic against lung and prostate cancer cell lines and cytotoxic against prostate cancer cell lines in vitro, although the dependence of RGS17 on these phenomena remains elusive, a result that is perhaps not surprising given the multimodal cytostatic and cytotoxic activities of many natural products.
|
28621943 |
2017 |
Malignant neoplasm of prostate
|
0.140 |
Biomarker
|
disease |
BEFREE |
RGS17: an emerging therapeutic target for lung and prostate cancers.
|
23734683 |
2013 |
Prostate carcinoma
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
|
23535732 |
2013 |
Prostate carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures.
|
29351497 |
2018 |
Prostate carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Our findings revealed that miR-203/RGS17 axis might be a potential therapeutic target for the treatment of PCa.
|
31298318 |
2019 |
Prostate carcinoma
|
0.130 |
Biomarker
|
disease |
BEFREE |
Two compounds, sanguinarine (1) and celastrol (2), were found to be cytostatic against lung and prostate cancer cell lines and cytotoxic against prostate cancer cell lines in vitro, although the dependence of RGS17 on these phenomena remains elusive, a result that is perhaps not surprising given the multimodal cytostatic and cytotoxic activities of many natural products.
|
28621943 |
2017 |
Prostate carcinoma
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
|
29892016 |
2018 |
Malignant neoplasm of lung
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
A region-wide scan across 6q23-25 found significant association between lung cancer susceptibility and three single nucleotide polymorphisms in the first intron of the RGS17 gene.
|
19351763 |
2009 |
Malignant neoplasm of lung
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Taken together, these data have provided the first evidence of miRNA regulation of RGS17 expression in lung cancer.
|
20420807 |
2010 |
Malignant neoplasm of lung
|
0.050 |
Biomarker
|
disease |
BEFREE |
Besides, miRNA-199 may inhibit the malignant progression of LCa by interacting with RGS17.
|
31081094 |
2019 |
Malignant neoplasm of lung
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Increased RGS17 expression in some prostate and lung cancers has been demonstrated to support cancer progression, while reduced expression of RGS17 can lead to development of chemotherapeutic resistance in ovarian cancer.
|
23734683 |
2013 |
Malignant neoplasm of lung
|
0.050 |
Biomarker
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNP) on chromosomal regions 5p15.33, 6p21.33, 6q23-25/RGS17, and 15q24-25.1 were assessed for their associations with familial lung cancer.
|
20142248 |
2010 |
Carcinoma of lung
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Taken together, these data have provided the first evidence of miRNA regulation of RGS17 expression in lung cancer.
|
20420807 |
2010 |
Carcinoma of lung
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
A region-wide scan across 6q23-25 found significant association between lung cancer susceptibility and three single nucleotide polymorphisms in the first intron of the RGS17 gene.
|
19351763 |
2009 |
Carcinoma of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNP) on chromosomal regions 5p15.33, 6p21.33, 6q23-25/RGS17, and 15q24-25.1 were assessed for their associations with familial lung cancer.
|
20142248 |
2010 |
Carcinoma of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Besides, miRNA-199 may inhibit the malignant progression of LCa by interacting with RGS17.
|
31081094 |
2019 |
Primary malignant neoplasm of lung
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Taken together, these data have provided the first evidence of miRNA regulation of RGS17 expression in lung cancer.
|
20420807 |
2010 |
Primary malignant neoplasm of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Besides, miRNA-199 may inhibit the malignant progression of LCa by interacting with RGS17.
|
31081094 |
2019 |