|
Colorectal Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These data suggest that RGS17 is overexpressed in colorectal carcinoma and promotes cell proliferation, migration, and invasion.
|
28337960 |
2018 |
|
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
We studied the role of the regulator of G-protein signaling (RGS) family of proteins RGS17 in colorectal carcinoma growth and metastasis.
|
28337960 |
2018 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
RGS17 plays an important role in the regulation of cancer cell proliferation, migration and invasion.
|
29559347 |
2018 |
|
Liver carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
RGS17 overexpression promoted HCC cell proliferation, migration, and invasion, and reversed the miR-199 mediated inhibition of proliferation, migration, and invasion.
|
29559347 |
2018 |
|
Nasopharyngeal carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In vivo, RGS17 also inhibits the tumorigenicity of NPC.
|
30464507 |
2018 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
To understand the role of miRNAs in Regulator of G Protein Signaling 17 (RGS17)-induced NSCLC, we showed that miR-203 was downregulated during tumorigenesis, and inhibited the proliferation and invasion of lung cancer cells.
|
28921827 |
2017 |
|
Tumor Progression
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Increased RGS17 expression in some prostate and lung cancers has been demonstrated to support cancer progression, while reduced expression of RGS17 can lead to development of chemotherapeutic resistance in ovarian cancer.
|
23734683 |
2013 |
|
Substance Dependence
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The association of 13 RGS17 and eight RGS20 tag single nucleotide polymorphisms (SNPs) was examined with four substance dependence diagnoses (alcohol (AD), cocaine (CD), opioid (OD) or marijuana (MjD)] in 1,905 African Americans (AAs: 1,562 cases and 343 controls) and 1,332 European Americans (EAs: 981 cases and 351 controls).
|
22591552 |
2012 |
|
Adenocarcinoma of lung (disorder)
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
RGS17 is previously shown to be over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth.
|
20420807 |
2010 |
|
Prostatic Neoplasms
|
0.010 |
AlteredExpression
|
group |
LHGDN |
Through microarray and gene expression analysis, we show that expression of RGS17 is up-regulated in 80% of lung tumors, and also up-regulated in prostate tumors.
|
19244110 |
2009 |
|
Familial (FPAH)
|
0.010 |
Biomarker
|
disease |
BEFREE |
RGS17 is a major candidate for the familial lung cancer susceptibility locus on chromosome 6q23-25.
|
19351763 |
2009 |
|
Malignant neoplasm of breast
|
0.010 |
Biomarker
|
disease |
BEFREE |
We have experimentally verified the presence of a previously unknown IRA1/RGS17 fusion in the breast cancer cell line MCF7.
|
15326299 |
2004 |
|
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
We have experimentally verified the presence of a previously unknown IRA1/RGS17 fusion in the breast cancer cell line MCF7.
|
15326299 |
2004 |
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
In searching for potential downstream targets of miR-203, a regulator of G-protein signaling 17 (RGS17) entered our sight due to its active role in a variety of malignant tumors.
|
31298318 |
2019 |
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
RGS17 plays an important role in the regulation of cancer cell proliferation, migration and invasion.
|
29559347 |
2018 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Subsequently colony formation assays and CCK8 cell viability assay was used to test the proliferation of NPC cells, flow cytometry was used to determine the percentage of apoptotic cells, MMP kit and flow cytometry was used to measure the mitochondrial membrane potential, and a xenograft tumour model was attached to investigate the effects of RGS17 on the growth of NPC cells in vivo.
|
30464507 |
2018 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
G-Protein Signaling Protein-17 (RGS17) Is Upregulated and Promotes Tumor Growth and Migration in Human Colorectal Carcinoma.
|
28337960 |
2018 |
|
Carcinogenesis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma.
|
30464507 |
2018 |
|
Lung Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
RGS17 is previously shown to be over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth.
|
20420807 |
2010 |
|
Lung Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Human lung tumor cell proliferation and tumorigenesis in nude mice are inhibited upon knockdown of RGS17 levels.
|
19351763 |
2009 |
|
Carcinogenesis
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
Human lung tumor cell proliferation and tumorigenesis in nude mice are inhibited upon knockdown of RGS17 levels.
|
19351763 |
2009 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
RGS17 plays an important role in the regulation of cancer cell proliferation, migration and invasion.
|
29559347 |
2018 |
|
Tumor Cell Invasion
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
These data suggest that RGS17 is overexpressed in colorectal carcinoma and promotes cell proliferation, migration, and invasion.
|
28337960 |
2018 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
To understand the role of miRNAs in Regulator of G Protein Signaling 17 (RGS17)-induced NSCLC, we showed that miR-203 was downregulated during tumorigenesis, and inhibited the proliferation and invasion of lung cancer cells.
|
28921827 |
2017 |
|
Carcinoma of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Besides, miRNA-199 may inhibit the malignant progression of LCa by interacting with RGS17.
|
31081094 |
2019 |