GHR, growth hormone receptor, 2690

N. diseases: 247; N. variants: 46
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Therefore, we present in vitro, in vivo, and in silico evidence which strongly implicates the GH-GHR axis in inducing chemoresistance in human melanoma by driving MITF-regulated and ABC-transporter-mediated drug clearance pathways. 31547367 2019
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Recent reports have confirmed highest levels of growth hormone (GH) receptor (GHR) transcripts in melanoma, one of the most aggressive forms of human cancer. 28223541 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.040 Biomarker disease BEFREE Due to the novel finding of high GHR in melanoma, we examined the effect of GH treatment on three NCI60 melanoma lines (MDA-MB-435, UACC-62 and SK-MEL-5). 24134847 2013
CUI: C0025202
Disease: melanoma
melanoma 		0.040 AlteredExpression disease BEFREE Up-regulation of growth hormone receptor immunoreactivity in human melanoma. 10470136 1999