GHSR, growth hormone secretagogue receptor, 2693

N. diseases: 171; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020175
Disease: Hunger
Hunger
0.050 GeneticVariation phenotype BEFREE Ghrelin, also known as the 'hunger hormone,' has the unique ability to enter the CNS and interact with the growth hormone secretagogue receptor (GHS-R) within the hippocampus. 30443455 2018
CUI: C0020175
Disease: Hunger
Hunger
0.050 Biomarker phenotype BEFREE It is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the hypothalamus to signal hunger and promote food intake. 28959025 2017
CUI: C0020175
Disease: Hunger
Hunger
0.050 Biomarker phenotype BEFREE The growth hormone secretagogue receptor (GHSR) is mediating hunger sensation when stimulated by its natural ligand ghrelin. 20404923 2010
CUI: C0020175
Disease: Hunger
Hunger
0.050 GeneticVariation phenotype BEFREE Dietary restraint and disinhibition were associated with an SNP in GHSR (477G>A, P<0.05), and perceived hunger with SNPs in GHSR and NPY (477G>A and 204T>C, P<0.05). 18957934 2008
CUI: C0020175
Disease: Hunger
Hunger
0.050 GeneticVariation phenotype BEFREE Ghrelin receptor mutations--too little height and too much hunger. 16511600 2006