NOX1, NADPH oxidase 1, 27035

N. diseases: 142; N. variants: 3
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.030 Biomarker disease BEFREE In particular, the superoxide-generating type 1 NADPH oxidase (NOX1) has been shown to be induced and play a pivotal role in early phases of mouse models of atherosclerosis and in the context of diabetes mellitus. 26715682 2016
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.030 Biomarker disease BEFREE We and others demonstrated that NOX1/2 NADPH oxidase inhibition, by genetic deletion of p47phox, in Apoe(-/-) mice decreases vascular reactive oxygen species (ROS) generation and atherosclerosis in young age. 26054376 2015
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.030 AlteredExpression disease LHGDN Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome. 16380495 2006