NOX1, NADPH oxidase 1, 27035

N. diseases: 142; N. variants: 3
Disease: Cardiovascular Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 Biomarker group BEFREE Cardiovascular diseases are characterized by increased production of reactive oxygen species (ROS) by NAPDH oxidase 1 (Nox1) and additional Nox isoforms among other sources. 28343901 2018
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 Biomarker group BEFREE The present study examined whether NOX1/2 NADPH oxidases are also pivotal to aging-associated CVD. 26054376 2015
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.030 Biomarker group BEFREE Based on these findings and promising preclinical studies with the NOX1/NOX2 antagonist, apocynin, we suggest that the field is poised for clinical evaluation of NOX inhibitors as therapeutics for cardiovascular disease. 25066192 2014