NOX1, NADPH oxidase 1, 27035

N. diseases: 142; N. variants: 3
Disease: Cerebrovascular Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007820
Disease: Cerebrovascular Disorders
Cerebrovascular Disorders 		0.010 AlteredExpression group BEFREE These findings suggest the therapeutic potential of NDRs, which reduce Nox1 protein levels, not only for cardiovascular disease conditions including arterial hypertension, pulmonary hypertension, heart failure with preserved ejection fraction (HFpEF), and chronic renal disease, but also for other non-communicable diseases, such as cerebrovascular disease and vascular dementia, Alzheimer's disease, autoimmune diseases and cancer, in which elevated Nox1-derived ROS production plays a causal role. 31518594 2019