NOX1, NADPH oxidase 1, 27035

N. diseases: 142; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 Biomarker disease BEFREE Collectively, these data support the therapeutic potential for NOX-1 inhibition in diabetes. 28232183 2017
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 Biomarker disease BEFREE As dose-dependent and tissue-specific effects of the dual NOX1/4 inhibitor GKT137831 were observed, it is critical to define in further studies the relative balance of inhibiting NOX4 vs NOX1 in the micro- and macrovasculature in diabetes. 28160092 2017
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 Biomarker disease BEFREE NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes. 23801050 2013