NOX1, NADPH oxidase 1, 27035

N. diseases: 142; N. variants: 3
Disease: Leishmaniasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023281
Disease: Leishmaniasis
Leishmaniasis 		0.010 AlteredExpression disease BEFREE Moreover, Leishmania infection triggered cell proliferation as was evidenced by increased expression of cyclin A and p-RPS6. mTOR activation during Leishmania infection resulted in reduced expression of M1 macrophage markers (eg, ROS, NO, iNOS, NOX-1, IL-12, IL-1β and TNF-α), and increased expression of M2 macrophage markers (eg, arginase-1, IL-10, TGF-β, CD206 and CD163). 30187512 2018