NOX1, NADPH oxidase 1, 27035

N. diseases: 142; N. variants: 3
Disease: Pancreatitis, Chronic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic 		0.020 Biomarker disease BEFREE NADPH oxidase 1 mediates caerulein-induced pancreatic fibrosis in chronic pancreatitis. 31837426 2020
CUI: C0149521
Disease: Pancreatitis, Chronic
Pancreatitis, Chronic 		0.020 Biomarker disease BEFREE Recent evidence suggests that both NOX1 and DUOX2 species produce ROS in the gastrointestinal tract as a result of chronic inflammatory stress; cytokine induction (by interferon-γ, tumour necrosis factor α, and interleukins IL-4 and IL-13) of NOX1 and DUOX2 may contribute to the development of colorectal and pancreatic carcinomas in patients with inflammatory bowel disease and chronic pancreatitis, respectively. 25818486 2015