NOX1, NADPH oxidase 1, 27035

N. diseases: 142; N. variants: 3
Disease: Endothelial dysfunction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.040 Biomarker phenotype BEFREE Moreover, increased Nox1-derived O<sub>2</sub><sup>.-</sup> contributed to renal endothelial dysfunction in OZR. 31563085 2020
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.040 Biomarker phenotype BEFREE NOX1 and NOX5 are associated with endothelial dysfunction and inflammation but NOX4 has a protective effect on vascular function. 31345363 2019
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.040 AlteredExpression phenotype BEFREE Dh404 significantly attenuated endothelial dysfunction in diabetic Akita mice characterized by reduced contraction in response to phenylephrine and the downregulation of inflammatory genes (VCAM-1, ICAM-1, p65, IL-1β) and pro-oxidant genes (Nox1 and Nox2). 28253885 2017
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.040 Biomarker phenotype BEFREE Nox1/Nox2 promote the development of endothelial dysfunction, hypertension, and inflammation. 24180474 2014