BBC3, BCL2 binding component 3, 27113

N. diseases: 157; N. variants: 3
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 Biomarker disease BEFREE LDFRT reverses cisplatin resistance of SKOV3/DDP cells possibly by upregulating the expression of FOXO3a and its downstream target PUMA, suggesting that LDFRT might be a potent chemosensitizer for the treatment of ovarian cancer. 30941896 2019
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 Biomarker disease BEFREE Our previous study suggests a therapeutic potential of PUMA in treating ovarian cancer, however, the action mechanism of PUMA remains elusive. 28423586 2017
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.030 Biomarker disease BEFREE We sought to evaluate the therapeutic potential of p53 up-regulated modulator of apoptosis (PUMA) in ovarian cancer. 26698248 2015