DISC1, DISC1 scaffold protein, 27185

N. diseases: 136; N. variants: 44
Disease: Psychiatric symptom ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233401
Disease: Psychiatric symptom
Psychiatric symptom 		0.020 Biomarker phenotype BEFREE Taken together, our results suggest that nuclear DISC1 plays a critical role in the transcriptional regulation of D1R in the striatal neuron, providing a mechanistic link between DISC1 and dopamine-related psychiatric symptoms. 30915712 2019
CUI: C0233401
Disease: Psychiatric symptom
Psychiatric symptom 		0.020 Biomarker phenotype BEFREE Our findings provide new insights into the role of DISC1 in AD pathogenesis and link a potential function of DISC1 to the psychiatric symptoms of AD. 26062786 2016