DISC1, DISC1 scaffold protein, 27185

N. diseases: 136; N. variants: 44
Disease: Opiate Addiction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.030 GeneticVariation disease BEFREE An association between opioid dependence and DISC1 rs2738888 polymorphism has been recently reported. 26997180 2016
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.030 GeneticVariation disease BEFREE TSNAX-DISC1 SNP rs821722 (p = 1.46 × 10(-7)) was the most significant result with substantial contributions from both populations; we previously identified DISC1 associations with opioid dependence. 25555482 2015
CUI: C0524662
Disease: Opiate Addiction
Opiate Addiction 		0.030 GeneticVariation disease BEFREE This is the first demonstration that RVs affect the risk of OD and the first demonstration of biological convergence of schizophrenia and OD risk-via DISC1. 23855403 2014