DISC1, DISC1 scaffold protein, 27185

N. diseases: 136; N. variants: 44
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1510472
Disease: Drug Dependence
Drug Dependence
0.010 Biomarker group BEFREE To address the role of adolescent stress in the development of drug addiction, we combined a transgenic mouse model in which a putative dominant-negative form of DISC1 under expressional control of the prion protein promoter is used as a genetic risk factor and adolescent social isolation stress as a gene-environmental interaction (GXE). 30831136 2020