PDLIM3, PDZ and LIM domain 3, 27295

N. diseases: 118; N. variants: 4
Disease: Ankylosing spondylitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.020 AlteredExpression disease BEFREE ALP gene expression and intracellular ALP activity were analyzed in microarray data from primary diseases control (Ct) and AS-bone-derived cells (BdCs) and in vitro experiments. 30415492 2019
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.020 AlteredExpression disease BEFREE Intriguingly, blocking IL-17A with serum from patients with AS attenuated ALP activity and mineralization in both Ct and AS-BdCs by inhibiting JAK2 phosphorylation and downregulating osteoblast-involved genes. 29880011 2018