PDLIM3, PDZ and LIM domain 3, 27295

N. diseases: 118; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0342649
Disease: Vascular calcification
Vascular calcification
0.020 AlteredExpression phenotype BEFREE Ghrelin treatment attenuated the elevation of calcium deposition and ALP activity in VC model both in vivo and in vitro. 27916732 2017
CUI: C0342649
Disease: Vascular calcification
Vascular calcification
0.020 PosttranslationalModification phenotype BEFREE The present study showed that DNMT inhibitors facilitate the Pi-induced development of vascular calcification via the upregulation of the ALP expression along with a reduction in the DNA methylation level of the ALP promoter region. 24441913 2014